• In line with Government advice, please only come to the Campus if it is essential to be in the workplace. Thank you.
Skip to content

Principal Beamline Scientist – I03

View Full Job Details

We now have three new opportunities for Principal Beamline Scientists to join our team, including for an internationally recognised structural biologist and/or methods development expert to take up this role at group leader level for the I03 Beamline, to guide and develop the beamline.

Principal Beamline Scientist – I03

Harwell Science and Innovation Campus, Oxfordshire / Home working available

Salary £55,097 - £64,821, dependent upon skills and experience

Full time / Flexible hours considered.


About Us

Diamond Light Source is the UK’s national 3rd generation synchrotron science facility. By accelerating electrons to near light-speed, Diamond generates brilliant beams of light from infra-red to X-rays which are used for academic and industry research and development across a range of scientific disciplines including structural biology, physics, chemistry, materials science, engineering, earth and environmental sciences.

Diamond is one of the most advanced scientific facilities in the world, and its pioneering capabilities and talented staff are helping to keep the UK at the forefront of scientific research. 

About the Role

I03 is a state-of-the-art macromolecular crystallography beamline at Diamond, uniquely being capable of collecting data from crystalline samples up to biological containment level 3. Over its lifetime the team has led many of the developments for cryogenic sample automation at Diamond and undergone continual upgrades so that today it provides a highly automated, high throughput beamline for an international programme of MX users.

We now have three new opportunities for Principal Beamline Scientists to join our team, including for an internationally recognised structural biologist and/or methods development expert to take up this role at group leader level for the I03 Beamline, to guide and develop the beamline.

In the role of Principal Beamline Scientist (PBS) you will supervise a small team of scientists to establish a competitive research programme which exploits the capabilities of I03 and Diamond and contribute to the development and operation of the I03/MX group international user programme. 

The post is underpinned by funding for a post-doctoral research associate linked to the role, subject to a suitable case being made to support research and development within the group. Furthermore, Diamond has a successful PhD programme and is strategically partnered with a number of doctoral training centres across the UK providing the opportunity for PhD studentships (https://www.diamond.ac.uk/Careers/Students.html). You will have access to state-of-the-art laboratories for structural and cellular biology embedded at Diamond and within the Research Complex at Harwell to pursue your research.

Instrumentation and software development is facilitated by dedicated support from Diamonds computing, engineering and scientific software groups as well as partnerships with CCP4 and the recently established Rosalind Franklin Institute (who are close partners of the HeXI project) amongst others. We would expect candidates to apply for external grant funding through national and international funding agencies to take full advantage of the stimulating and exciting research environment at Diamond.

I03 is a fully tuneable energy beamline equipped with a state-of-the-art detector (Eiger2 XE 16M) and very high capacity, rapid sample changer (BART) enabling high throughput automated data collection capabilities for MX at Diamond. Looking to the future, the expected Diamond-II upgrade programme of machine and beamlines presents a unique opportunity for the post holder to develop methodologies and a complementary user programme for I03 for structural biology studies, where appropriate exploiting the beamlines unique biological containment level 3 capability.

The macromolecular crystallography (MX) group at Diamond comprises 7 world-class MX beamlines with unique capabilities and is complemented by dedicated beamlines for BIOSAXS, CD, X-ray imaging and spectroscopy, IR-microspectroscopy and the UK’s national Cryo-EM centre (eBIC). The MX group at Diamond established the first dedicated synchrotron-based labs for X-ray fragment screening (X-Chem) and membrane proteins (MPL). In addition, the UK XFEL hub provides a focus for XFEL work, engaging UK users in serial crystallography experiments around the world, and directs UK developments at the SPB/SFX instrument at the European XFEL. The MX group has a strong software development programme which includes development of the DIALS integration software package, ISPyB/SynchWeb and automation pipelines. 

About You

You will hold appropriate first and higher degrees or demonstrate significant equivalent experience.

You will be a highly talented structural biologist or methods development expert, with expertise in macromolecular crystallographic techniques as applied at synchrotron beamlines, and a broad outlook in structural biology.

Experience of beamline instrumentation and/or sample environment equipment, biological containment environments, and programming especially python and java, will benefit your application.

You will demonstrate skills in managing a small team, as well as a managing a budget and other resources for research and operations and upgrade projects.

You will have demonstrated ability to develop a research programme, and to lead significant projects.

You will display excellent interpersonal, communication and presentational skills, to interact effectively with staff and stakeholders at all levels.


Diamond offers an exceptional benefits package to support staff in achieving a positive work/life balance. This includes 25 days annual leave plus 13 days of statutory and company holidays, along with flexible working hours and an excellent pension scheme. Staff also have access to a range of amenities on site including a nursery, cafes, a restaurant and sports and leisure facilities. A relocation allowance may also be available where applicable.

To Apply

Applicants are required to outline their suitability for this role via the online application process. Please also state where you saw this role advertised.

Diamond is a thriving international organisation, attracting a diverse range of talented individuals from around the world. Our staff currently comprises 39 nationalities and we welcome applications from everyone interested in joining us.

The closing date for applications is 6th December 2020.


We use cookies to give you the best experience of using this website. By continuing to use this site, you accept our use of cookies. Please read our Cookie Policy for more information.